I have this issue on multiple computers now; both my desktop PC and my arcade machine. Both running Windows 10, same (new) build.
The escape <esc> key no longer seems responsive in exiting a game (or the main program). This is NOT related to the new build; I've seen it now for the last couple of builds. I thought it was just me, or related to my arcade setup front end (AttractMode). But now I'm seeing it on my normal PC, just running Aracade64 by itself. I have to hit <esc> over and over again for it to react.
I've tried un-mapping and re-mapping it, with the same effect.
Is anyone else seeing this? I think it's a MAME (core) issue, not an Arcade64 issue, but I'd like to see if anyone else has noticed this behavior.